Nasser Rusan: Scoping out centrosomes

PLP helps the mother centrosome stay mum

PLP helps the mother centrosome stay mum D rosophila neuroblasts give rise to the fl y's central nervous system by dividing asymmetrically to produce a daughter neuroblast and a gan-glion mother cell (GMC). The neuroblast's centrosomes are themselves asymmetric in terms of their activity, localization, and pattern of inheritance. Lerit and Rusan describe how the centrosomal protein pericentrin ...

SCOPing out Proteases in Long-Term Memory

The ERK1/2 MAP kinase (MAPK) signaling pathway is important for the formation of long-term memories. In this issue, Shimizu et al. (2007) provide new insight into the regulation of this pathway by demonstrating that activation of MAP kinase occurs through the calcium-dependent degradation of SCOP (suprachiasmatic nucleus circadian oscillatory protein) by the protease calpain.

11 Complex Hydrocephalus Nasser

Hydrocephalus arising from intraventricular septations is known as complex or loculated hydrocephalus. Many synonyms for complex hydrocephalus have been used in the literature such as compartmentalized or loculated hydrocephalus. Complex hydrocephalus remains a challenging neurosurgical problem. Definitive treatment is surgical, yet the approach remains controversial. Traditional treatment cons...

Research Description Nasser Soliman Demir

In the first few microseconds following the Big Bang, the very hot and dense Universe was thought to be in a state of matter known as the quark gluon plasma (QGP). The QGP is rather different from the normal matter we observe everyday; protons and neutrons are examples of particles in which quarks and gluons are bound. It is said that quarks and gluons are confined in Nature; we do not observe ...

9 - 1 - 2010 Clinical – Pathological Conference : Case 2 Nasser